Annette received a prestigious Veni award from NWO. With her grant she will study a hidden identity: macrophage-to-myofibroblast transdifferentiation in atherosclerosis


Macrophages are key immune regulators of atherosclerosis. Annette will study a novel mechanism by which macrophages contribute to disease, via transdifferentiation into myofibroblast-like cells. These transdifferentiated cells acquire characteristics that contribute to atherosclerotic plaque stability, an undescribed feature for macrophages. Applying cell-culture systems, the researcher will identify regulators and mechanisms that contribute to transdifferentiation of macrophages in atherosclerosis.

Share this message

Latest news Medical Biochemistry Amsterdam

October 24, 2025
Vidi for Marten Hoeksema!
October 24, 2025
Congratulations to dr. Aukie Hooglugt for finishing his PhD
Show More