Annette received a prestigious Veni award from NWO. With her grant she will study a hidden identity: macrophage-to-myofibroblast transdifferentiation in atherosclerosis
Macrophages are key immune regulators of atherosclerosis. Annette will study a novel mechanism by which macrophages contribute to disease, via transdifferentiation into myofibroblast-like cells. These transdifferentiated cells acquire characteristics that contribute to atherosclerotic plaque stability, an undescribed feature for macrophages. Applying cell-culture systems, the researcher will identify regulators and mechanisms that contribute to transdifferentiation of macrophages in atherosclerosis.
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Latest news Medical Biochemistry Amsterdam
The AGEM PhD retreat was held on the 3 rd and 4 th of April in Garderen. The theme of the Research Institute was fully centered with interesting presentations by PhDs and guest speakers. Ilaria Micallo, one of our PhD candidates from Noam Zelcer’s group, obtained the Best Poster Award for her research on “Structural basis for substrate selectivity by site-one protease revealed by studies with a small molecule inhibitor” .
Karen and Panos got awarded the Amsterdam UMC Young Talent Fund . This fund awards young PhD talents a chance to further develop and enhance their skills, with the aim to provide the opportunity for PhD candidates to do an internship or follow a course at top international research institutes.
