The Zelcer lab's study describing the structure of SPRING and S1P is out. This was a great collaboration with Daniel Kober (UTSW) who is a biochemsitry and CryoEM wizard. This study provides th structural basis for the role SPRING has in proteolytic maturation of the S1P zymogen, and why SPRING is required for S1P-mediated cleavage of the SREBP transcription factors. Enjoy the reading and let us know what you think of this:
https://www.nature.com/articles/s41467-024-50068-8
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Latest news Medical Biochemistry Amsterdam
At the annual symposium of the Amsterdam institute for Immunology and Infectious diseases (AII), Guillermo Griffith has won the best poster award within the Immunology program. Congrats, Guillermo!!
On June 17th, Amber Meurs successfully defended her PhD thesis “A cycle of trasport and regulation - unveiling the hidden routes of cellular cholesterol transport” at the University of Amsterdam.
