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The Zelcer lab's study describing the structure of SPRING and S1P is out. This was a great collaboration with Daniel Kober (UTSW) who is a biochemsitry and CryoEM wizard. This study provides th structural basis for the role SPRING has in proteolytic maturation of the S1P zymogen, and why SPRING is required for S1P-mediated cleavage of the SREBP transcription factors. Enjoy the reading and let us know what you think of this:

https://www.nature.com/articles/s41467-024-50068-8


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Latest news Medical Biochemistry Amsterdam

By duda-wsm March 26, 2025
Karen and Panos got awarded the Amsterdam UMC Young Talent Fund . This fund awards young PhD talents a chance to further develop and enhance their skills, with the aim to provide the opportunity for PhD candidates to do an internship or follow a course at top international research institutes.
By duda-wsm March 25, 2025
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