Another great paper in collaboration on SPRING-S1P with Daniel Kober’s team (UTSW) is bow out in PNAS. Using a neat series of biochemical, structural and cellular studies, Ashley Bullington and Ilaria Micallo studied how the SPRING-S1P complex recognize its substrates and promotes their cleavage. You can get the paper on https://www.pnas.org/doi/full/10.1073/pnas.2426931122 or www.zelcerlab.eu
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Latest news Medical Biochemistry Amsterdam
Paper accepted in Current Opinion in Lipidology! Our review article together with Daniel Kober’s group (UTSW) summarizing recent mechanistic and structural findings on the SPRING-S1P-SREBP axis is now out. If you want to understand how this system works have a look. Congrats to Ilaria Micallo and Ashley Bullington for putting this together!
