Logo
Stephan Huveneers • March 8, 2023

Huveneers lab publishes about angiogenesis in Nature Communications

Researchers from the Huveneers lab at Amsterdam UMC, together with international collaborators from the Universities of Cologne and Barcelona, published their latests findings on dedicated molecular signals in angiogenesis in Nature Communications.


Angiogenesis, the formation of new blood vessels, is an essential physiological process for development, wound healing and tumorigenesis. To make new blood vessels, endothelial cells move as a collective. The movement of endothelial cells is triggered by so-called leaders that connect to followers. Researchers from the Huveneers lab at Amsterdam UMC, together with international collaborators from the Universities of Cologne and Barcelona, have now discovered dedicated molecular signals that originate at the contact interface between the leader and follower cells. By using fluorescence microscopy those signals were captured during endothelial cell migration, which revealed that they guide follower cells. The results of this study offer important insights and new perspectives that may help to develop approaches that target angiogenesis in patients. The findings were published in Nature Communications. Visit the Nature Communications website for the full article.

Share this message

Latest news Medical Biochemistry Amsterdam

By Marten Hoeksema December 2, 2024
Both Alexandra and Ricky received travel grant awards to join the EMDS in beautiful Vienna! Here they presented their research to dozens of macrophage experts!
By duda-wsm November 6, 2024
Marten Hoeksema received a Bertus Kemp Stipendium from the " Genootschap ter bevordering van Natuur-, Genees- en Heelkunde ". The aim is to study kinase activity differences in macrophages activated with various cytokines. The grant will be used for this research as well as a work visit to the lab of collaborator dr. Emiel van der Vorst at the university of Aachen.
Show More
Share by: