Deletion of EEPD1 reveals macrophage-specific changes in lipid metabolism and cholesterol efflux

Just in before the PhD defence, Suzanne latest publication on EEPD1 was accepted for publication in “Atherosclerosis” (https://www.atherosclerosis-journal.com/article/S0021-9150(25)00060-7/fulltext). This study describes the metabolic phenotype of mice and macrophages lacking EEPD1. This study reveals that mice lacking EEPD1 are susceptible to weight gain when challenged with a fat containing diet, cements the role of EEPD1 in cholesterol efflux, and identifies marked lipidomic changes in macrophages in the absence of EEPD1.