Deletion of EEPD1 reveals macrophage-specific changes in lipid metabolism and cholesterol efflux
Just in before the PhD defence, Suzanne latest publication on EEPD1 was accepted for publication in “Atherosclerosis” (https://www.atherosclerosis-journal.com/article/S0021-9150(25)00060-7/fulltext). This study describes the metabolic phenotype of mice and macrophages lacking EEPD1. This study reveals that mice lacking EEPD1 are susceptible to weight gain when challenged with a fat containing diet, cements the role of EEPD1 in cholesterol efflux, and identifies marked lipidomic changes in macrophages in the absence of EEPD1.
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Latest news Medical Biochemistry Amsterdam
The AGEM PhD retreat was held on the 3 rd and 4 th of April in Garderen. The theme of the Research Institute was fully centered with interesting presentations by PhDs and guest speakers. Ilaria Micallo, one of our PhD candidates from Noam Zelcer’s group, obtained the Best Poster Award for her research on “Structural basis for substrate selectivity by site-one protease revealed by studies with a small molecule inhibitor” .
Karen and Panos got awarded the Amsterdam UMC Young Talent Fund . This fund awards young PhD talents a chance to further develop and enhance their skills, with the aim to provide the opportunity for PhD candidates to do an internship or follow a course at top international research institutes.
