• Carlie de Vries

    Medical Cell 

    Biochemistry

    Knop

Medical Cell Biochemistry

We aim to unravel the function of the nuclear hormone receptor Nur77 and its co-regulator the LIM domain-only protein FHL2 in atherosclerosis and obesity. Detailed molecular studies are performed to understand the molecular mechanisms of protein-protein interactions in transcriptional regulation.


Carlie de Vries

Medical Cell Biochemistry

c.j.devries@amsterdamumc.nl

Paper accepted on the interaction between SPRING and S1P!

By duda-wsm • May 6, 2025
Another great paper in collaboration on SPRING-S1P with Daniel Kober’s team (UTSW) is bow out in PNAS. Using a neat series of biochemical, structural and cellular studies, Ashley Bullington and Ilaria Micallo studied how the SPRING-S1P complex recognize its substrates and promotes their cleavage. You can get the paper on https://www.pnas.org/doi/full/10.1073/pnas.2426931122 or www.zelcerlab.eu

Best Poster Award for Ilaria

By duda-wsm • April 8, 2025
The AGEM PhD retreat was held on the 3 rd and 4 th of April in Garderen. The theme of the Research Institute was fully centered with interesting presentations by PhDs and guest speakers. Ilaria Micallo, one of our PhD candidates from Noam Zelcer’s group, obtained the Best Poster Award for her research on “Structural basis for substrate selectivity by site-one protease revealed by studies with a small molecule inhibitor” .
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Research

Medical Cell Biochemistry

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My Team

Medical Cell Biochemistry

Carlie de Vries

Person 1

Medical Cell Biochemistry

Menno De Winther

Person 2

Vascular Immunology

Person 3

Lipid Metabolism

Carlie de Vries

Medical Cell Biochemistry

Menno De Winther

Person 5

Vascular Immunology

Person 6

Lipid Metabolism

Publications

Medical Cell Biochemistry

Publication 1

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Medical Cell Biochemistry

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