Sebastian Hendrix (group Zelcer) et al. demonstrate in this Molecular and Cellular Biology paper that activity of SPRING is specific for S1P-mediated activation of SREBP and not of other transcription factors like Atf6!
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Latest news Medical Biochemistry Amsterdam
Paper accepted in Current Opinion in Lipidology! Our review article together with Daniel Kober’s group (UTSW) summarizing recent mechanistic and structural findings on the SPRING-S1P-SREBP axis is now out. If you want to understand how this system works have a look. Congrats to Ilaria Micallo and Ashley Bullington for putting this together!
